301 Main is in the heart of Downtown Ames; just steps away from shopping, restaurants, green space and exciting events. A five-minute drive from Iowa State University, 301 Main offers residents a prime distance from busy campus traffic, without the both of a long commute. Residential units start at $900 (including all utilities!), each unit includes hardwood floors, granite countertops, classic tile in kitchen and bath, and stainless steel appliances. The commercial spaces at 301 Main are unique and a perfect fit for retail and food service businesses looking to be a part of the bustling Downtown Ames community.

Originally constructed in 1915–1916, 301 Main Street was home to the iconic Sheldon-Munn Hotel, developed by local leaders including Parley Sheldon and the Munn family. When it opened in 1916, the four-story hotel quickly became the social and cultural hub of Ames, hosting community events, university gatherings, and visitors from across the region. Featuring over 100 guest rooms, a grand ballroom, and multiple dining spaces, it was considered one of the finest hotels in the Midwest at the time. Today, the historic building has been thoughtfully renovated, continuing its legacy as a vibrant part of downtown Ames.